SISU Hospital

Intrauterine Insemination

IUI

IUI is the simplest form of ART, in which washed, highly motile, capacitated /sperms are infused inside the uterus through a flexible catheter to improve the pregnancy rate.

This is indicated for any reasons:

  • Moderate Male Factor Infertility
  • Low Count
  • Penile abnormalities( Epispadias,Hypospadias)
  • Retrograde ejaculation(ejaculation backside)
  • Unexplained Infertility
  • Hostile Cervical Mucus. 

Unlike ICI, intrauterine insemination normally requires a medical practitioner to perform the procedure.  One of the requirements is to have at least one permeable tube, proved by hysterosalpingography.  The Infertility duration is also important.  A female under 30 years of age has optimal chances with IUI. For the man, a TMS of more than 5 million per ml is needed. A short period of ejaculatory abstinence before intrauterine insemination is associated with higher pregnancy rates.

IUI is a more efficient method of artificial insemination because it generally gives a higher success rate.  The success rate per cycle is 15% percent.

The patient needs to undergo hormonal evaluation, to know her ovarian function and at least one patent tube.  For husband, TMS should be more than 5 million/ml is optimal.

The patient’s ovary is stimulated with medicines and hormonal injections to produce more eggs.  Once the leading follicle is reached >18mm,and E2 >500pg/ml.   HCG injection was given.  The husband is advised to give semen.  After checking the count and motility it is been washed twice and capacitated with gradient technique.

Without anesthesia, the washed semen infused into the uterus with a flexible catheter.  The patient is advised to lie down for 15 minutes in the same position.

The success rate of IUI is 15% to 20% per cycle.