Obesity in women has impacts on fertility and fertility treatment. Increase in BMI reduces the chance of conception in ovulatory women and affects the outcome of ovulation induction treatment.
Obese women undergoing IVF require higher doses of gonadotrophins, respond poorly to ovarian stimulation and have fewer oocytes harvested. Obesity is associated with lower fertilization rates, poor quality embryos and higher miscarriage rates. Weight loss in these women improves their reproductive outcomes; however, in order for this to be effective it has to be gradual and sustained.